How Does Multiple Sclerosis Progress?
The first signs of multiple sclerosis (MS) usually appear between the ages of 20 and 50, though the disease can strike children and the elderly. Experts believe multiple sclerosis begins when the immune system is triggered to attack and break down myelin, the protective coating around nerve fibers. Rich in protein and fatty substances, myelin acts as insulation for the nerve fibers, which are called axons. Myelin helps the axons transmit signals from the central nervous system to other parts of the body. These signals control our physical functions and thinking abilities. When myelin is lost or damaged, the transfer of nerve impulses to and from the brain is disrupted and nerve tissue can become inflamed. This inflammation is what causes multiple sclerosis symptoms to appear and is known as a relapse. During a relapse, you may experience some physical disability and/or cognitive impairment, such as trouble with memory or problem solving. Visit our MS symptoms pages to learn more.

When the inflammation subsides, the symptoms of multiple sclerosis may subside as well. This period is known as a remission.
Physical disability is one way to mark the progression of disease in multiple sclerosis. However MS can also progress silently through the loss of axons. The brain can compensate for some level of damage, so symptoms may be hidden for quite some time. You actually could have multiple sclerosis, yet still feel perfectly healthy.
Like an iceberg, the progression of MS can lie concealed beneath the surface.

Because multiple sclerosis can progress silently, it’s essential to keep up with your MS treatment. While there is no cure for multiple sclerosis, treatment can reduce relapses, and some treatments have been proven to slow the progression of physical disability.
